Testing Protocol
Analytical quality control involves the periodic analysis of a check standard to confirm the validity of an initial calibration. This continuous calibration verification requires the operator to measure a known concentration at fixed intervals throughout a batch. Reliability depends on the stability of the detector and the consistency of the sample introduction system.
If the result falls outside predefined limits, the data generated since the last successful check becomes suspect.
Sampling Frequency
Regular testing intervals prevent the loss of large datasets when drift occurs. A continuous calibration verification usually follows every ten samples or occurs at the end of a sequence. This schedule ensures that instrument performance stays within acceptable bounds over an extended period.
Recovery Limit
Acceptable recovery for the check standard often sits between ninety and one hundred and ten percent of the true value. Environmental factors influence stability, yet continuous calibration verification identifies when these shifts exceed the method requirements.
Validation Requirement
Failure to meet the verification criteria necessitates a full recalibration of the sensor or system. Any samples processed between a failed continuous calibration verification and the previous passing check must undergo reanalysis. This procedure maintains the integrity of the measurement chain.
